Description
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🔬 Science & Mechanism
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) originally developed in Russia.
- Stimulates telomerase activation, helping maintain telomere length.
- Supports melatonin secretion and circadian rhythm regulation.
- Exhibits antioxidant and anti-carcinogenic properties in lab studies.
📊 Clinical Evidence
- Russian studies (Khavinson et al.) reported increased lifespan in animals and improved biomarkers in humans.
- Trials in elderly patients showed immune system improvements and restored melatonin cycles.
- Still considered experimental, but widely used in anti-aging clinics worldwide.
💉 Dosing Guide (Educational)
Reported Protocols:
- Typical cycle: 5–10 mg daily for 10–20 days, repeat 1–2x yearly.
- Often administered subcutaneously or intramuscularly.
💧 Reconstitution (10 mg vial + 2 mL BAC water)
- Final concentration = 5 mg/mL
- On insulin syringe (100 units = 1 mL): 50 mcg per unit
| Desired Dose | Volume (mL) | Syringe Units |
| 2.5 mg | 0.50 mL | 50 units |
| 5.0 mg | 1.00 mL | 100 units |
| 10 mg | 2.00 mL | 200 units |
🧊 Storage
- Store lyophilized vials refrigerated (2–8 °C).
- After reconstitution, refrigerate and use within 30 days.
- Protect from light.
❓ FAQ
Does Epithalon really lengthen telomeres?
Animal and early human trials suggest telomere lengthening, but more research is needed for conclusive proof.
How often should I run a cycle?
Most reported protocols use short courses (10–20 days), 1–2 times per year.
Can it help with sleep?
Yes—studies show Epithalon may regulate melatonin secretion and circadian rhythm.
⚠️ Disclaimer
- For educational purposes only.
- Not FDA or Health Canada approved for anti-aging use.
- Customers assume responsibility for safe handling.
📚 References
- Khavinson V, et al. Epithalamin and Epitalon: peptide geroprotectors. Biogerontology. 2003.
🔗 https://pubmed.ncbi.nlm.nih.gov/14501189/ - Anisimov VN, et al. Effect of Epitalon on lifespan and spontaneous tumor incidence in rats. Mech Ageing Dev. 2003.
🔗 https://pubmed.ncbi.nlm.nih.gov/12663200/ - Khavinson V, et al. Telomerase-activating effects of Epithalon in human somatic cells. Bull Exp Biol Med. 2003.
🔗 https://pubmed.ncbi.nlm.nih.gov/12937682/ - Arutyunyan R, et al. Epithalamin and melatonin secretion regulation in aging. Neuroendocrinol Lett. 2001.
🔗 https://pubmed.ncbi.nlm.nih.gov/11455349/


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